Designed the seismic retrofit of this 100,000 square foot Chemistry Annex Building. This five-story plus one-story basement, cast-in-place building is a heavy waffle slab and shear wall concrete structure supported on deep foundations. The building which had previously been determined to be “very poor” under the UC Seismic Policy was retrofit while occupied to largely preserve chemistry teaching and lab space, faculty offices and ongoing research. A nonlinear pushover analysis was used to minimize the retrofit and impact to the interior space. The retrofit includes vertical exterior concrete elements, interior column fiber wrapping, the addition of some shear walls at the basement level, and a new pier cap around the base of the building connecting the existing caissons together, and enhanced connection between the existing caissons and the foundation walls for seismic tension.